December Release - 12/05/2016
This release of RxNorm is consistent with the 2016AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm technical documentation.
Sources
The following sources have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| DrugBank | DRUGBANK | DRUGBANK5.0_2016_11_08 |
| Gold Standard Drug Database | GS | GS_2016_11_04 |
| Medi-Span Master Drug Data Base | MDDB | MDDB_2016_11_02 |
| Multum MediSource Lexicon | MMSL | MMSL_2016_11_01 |
| Micromedex RED BOOK | MMX | MMX_2016_11_14 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2016_11_28 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2016_11_09 |
| Veterans Health Administration National Drug File | VANDF | VANDF_2016_10_20 |
The following sources have not been updated in this release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2016 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2014 |
| Medical Subject Headings (MeSH) | MSH | MSH2017_2016_08_12 |
| Veterans Health Administration National Drug File - Reference Terminology | NDFRT | NDFRT_2016_11_07 |
| NDFRT FDASPL relationships | NDFRT_FDASPL | NDFRT_FDASPL_2016_11_07 |
| NDFRT FMTSME relationships | NDFRT_FMTSME | NDFRT_FMTSME_2016_11_07 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2016_07_31 |
Data Changes
This release includes many changes to dose forms for injectable products as part of the ongoing prescribable names (TTY=PSN) work.
New Data Source Included
The National Library of Medicine (NLM) is pleased to announce the addition of a new data source - DrugBank. The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The DrugBank dataset in RxNorm includes nearly 14,000 ingredient/chemical names and synonyms, along with the DrugBank ID for each.
New Dose Form Added
RxNorm includes a new dose form: Intrauterine System. This dose form is defined as a drug delivery system inserted and left in the uterus to provide uniform release of drugs over several years. Drugs with the new dose form used the Drug Implant dose form prior to the December release. This change affects four SBD concepts and their related graphs.
Qualitative Distinction
Please see the technical documentation for an explanation of Qualitative Distinctions (QDs), which were first released in the August monthly release.
Here are the new concepts with QDs in the December release:
| RXCUI | TTY | String |
|---|---|---|
| 848208 | SCD | Augmented Betamethasone 0.0005 MG/MG Topical Gel |
| 848180 | SCD | Augmented Betamethasone 0.0005 MG/MG Topical Ointment |
| 848200 | SBD | Augmented Betamethasone 0.0005 MG/MG Topical Ointment [Diprolene] |
| 848176 | SCD | Augmented Betamethasone 0.5 MG/ML Topical Cream |
| 848195 | SBD | Augmented Betamethasone 0.5 MG/ML Topical Cream [Diprolene] |
| 848178 | SCD | Augmented Betamethasone 0.5 MG/ML Topical Lotion |
| 848197 | SBD | Augmented Betamethasone 0.5 MG/ML Topical Lotion [Diprolene] |
For each SCD or SBD with a QD, there is an associated attribute in RXNSAT with the attribute name (ATN) of 'RXN_QUALITATIVE_DISTINCTION'. The December release contains the following new attributes to match the QD strings found in the SCD and SBD normalized names:
- Augmented
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 373 |
| Active BPCKs | 429 |
| Active SCDs | 18820 |
| Active SBDs | 10658 |
| Active RXNORM MINs | 3983 |
| Active RXNORM INs | 11191 |
| Active RXNORM PINs | 2601 |
| Active RXNORM BNs | 6273 |
| Active RXNORM DFs | 115 |
| Obsolete GPCKs | 144 |
| Obsolete BPCKs | 129 |
| Obsolete SCDs | 16216 |
| Obsolete SBDs | 10206 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 9659 |
| Obsolete RXNORM DFs | 59 |
| Editor-suppressed SCDs | 1581 |
| Editor-suppressed SBDs | 1330 |
| Source-asserted NDCs | 1235524 |
| Distinct source-asserted NDCs | 582456 |
| SAB=RXNORM NDCs | 221854 |
| Distinct SAB=RXNORM NDCs | 221854 |
Last Reviewed: February 6, 2017