April Release - 4/06/2020
This full release of RxNorm is consistent with the 2019AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Vaccines Administered | CVX | CVX_2020_02_12 |
| DrugBank | DRUGBANK | DRUGBANK5.0_2020_02_27 |
| Gold Standard Drug Database | GS | GS_2020_03_26 |
| Multum MediSource Lexicon | MMSL | MMSL_2020_03_01 |
| Micromedex RED BOOK | MMX | MMX_2020_03_09 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2020_03_28 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2020_04_01 |
| RxNorm normalized names and codes | RXNORM | RRXNORM_19AB_200406F |
| Veterans Health Administration National Drug File | VANDF | VANDF_2020_02_28 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2020 |
| Medical Subject Headings (MeSH) | MSH | MSH2020_2019_08_27 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2014 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2020_01_31 |
| USP Compendial Nomenclature | USP | USP_2020_02_06 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
Data Changes
Investigational Drugs in RxNormIn March 2020, the World Health Organization declared the Coronavirus disease (COVID-19) a pandemic. Because of this significant public health concern, we have reexamined the scope of RxNorm. As a result, the April 2020 release of RxNorm contains the following investigational drug information:
- Ingredient (IN): remdesivir (RXCUI 2284718); and
- Semantic Clinical Drug (SCD): remdesivir 100 MG Injection (RXCUI 2284960)
For more information about this RxNorm policy change, see the following NLM Technical Bulletin: https://www.nlm.nih.gov/pubs/techbull/ma20/ma20_rx_norm_investigational_drugs.html
Dose Form ChangesTwo new dose forms are available starting with the April 2020 release. The new dose forms are:
- Delayed Release Oral Granules; and
- Inhalation Spray
Inhalation Spray and Metered Dose Inhaler are both valid RxNorm dose forms. For certain medications, Inhalation Spray replaced the Metered Dose Inhaler dose form while retaining the same RXCUI. Here are the new prescribable drug names where Inhalation Spray replaced Metered Dose Inhaler:
| RXCUI | TTY | String |
|---|---|---|
| 1190220 | SCD | 120 ACTUAT Albuterol 0.1 MG/ACTUAT / Ipratropium Bromide 0.02 MG/ACTUAT Inhalation Spray |
| 1190225 | SBD | 120 ACTUAT Albuterol 0.1 MG/ACTUAT / Ipratropium Bromide 0.02 MG/ACTUAT Inhalation Spray [Combivent] |
| 836286 | SCD | 200 ACTUAT Albuterol 0.09 MG/ACTUAT / Ipratropium Bromide 0.018 MG/ACTUAT Inhalation Spray |
| 836366 | SBD | 200 ACTUAT Albuterol 0.09 MG/ACTUAT / Ipratropium Bromide 0.018 MG/ACTUAT Inhalation Spray [Combivent] |
| 1546077 | SCD | 28 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray |
| 1546079 | SBD | 28 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray [Striverdi] |
| 1546082 | SCD | 60 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray |
| 1546083 | SBD | 60 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray [Striverdi] |
| 2166203 | SCD | 10 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray |
| 2166204 | SBD | 10 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Spiriva] |
| 1552008 | SCD | 28 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray |
| 1552009 | SBD | 28 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Spiriva] |
| 1552002 | SCD | 60 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray |
| 1552004 | SBD | 60 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Spiriva] |
| 1667885 | SCD | 28 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray |
| 1667886 | SBD | 28 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray [Spiriva] |
| 1667880 | SCD | 60 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray |
| 1667882 | SBD | 60 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray [Spiriva] |
| 2166927 | SCD | 10 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray |
| 2166928 | SBD | 10 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Stiolto] |
| 1651266 | SCD | 28 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray |
| 1651271 | SBD | 28 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Stiolto] |
| 1651274 | SCD | 60 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray |
| 1651275 | SBD | 60 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Stiolto] |
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 439 |
| Active BPCKs | 522 |
| Active SCDs | 17265 |
| Active SBDs | 9949 |
| Active RXNORM MINs | 3742 |
| Active RXNORM INs | 12500 |
| Active RXNORM PINs | 2962 |
| Active RXNORM BNs | 5581 |
| Active RXNORM DFs | 121 |
| Obsolete GPCKs | 208 |
| Obsolete BPCKs | 185 |
| Obsolete SCDs | 17562 |
| Obsolete SBDs | 11139 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6343 |
| Obsolete RXNORM DFs | 62 |
| Editor-suppressed SCDs | 1756 |
| Editor-suppressed SBDs | 1479 |
| SAB=RXNORM NDCs | 238628 |
| Distinct SAB=RXNORM NDCs | 238628 |
Last Reviewed: April 9, 2020