April Release - 04/05/2021
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| DrugBank | DRUGBANK | DRUGBANK5.0_2021_02_26 |
| Gold Standard Drug Database | GS | GS_2021_03_10 |
| Multum MediSource Lexicon | MMSL | MMSL_2021_03_01 |
| Micromedex RED BOOK | MMX | MMX_2021_03_08 |
| Medical Subject Headings (MeSH) | MSH | MSH2021_2021_01_25 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2021_03_26 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2021_03_10 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_210405F |
| USP Compendial Nomenclature | USP | USP_2021_03_15 |
| Veterans Health Administration National Drug File | VANDF | VANDF_2021_02_28 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2021 |
| Vaccines Administered | CVX | CVX_2021_01_29 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2021_01_31 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RXNORM DATA CHANGES
New Qualitative Distinction
Qualitative Distinction (QD) modifiers allow flexibility in the RxNorm model to create a new RxNorm Concept Unique Identifier (RXCUI) or differentiate an existing medication concept when needed. The new QD modifier “PMDD” distinguishes products indicated for the treatment of premenstrual dysphoric disorder (PMDD).
The April 2021 release includes the new “PMDD” QD for the following active concepts:
| RXCUI | TTY | String |
|---|---|---|
| 2532159 | SCD | PMDD fluoxetine 10 MG Oral Tablet |
| 647555 | SBD | PMDD fluoxetine 10 MG Oral Tablet [Sarafem] |
| 803293 | SCD | PMDD fluoxetine 15 MG Oral Tablet |
| 803295 | SBD | PMDD fluoxetine 15 MG Oral Tablet [Sarafem] |
| 2532163 | SCD | PMDD fluoxetine 20 MG Oral Tablet |
| 647556 | SBD | PMDD fluoxetine 20 MG Oral Tablet [Sarafem] |
For each SCD or SBD with a QD, there is an associated attribute in RXNSAT with the attribute name (ATN) of 'RXN_QUALITATIVE_DISTINCTION'. The April release contains the following new attribute value (ATV) to match the QD strings found in the SCD and SBD normalized names:
- PMDD
RELATED NEWS
Did you know that RxClass includes Med-RT content, such as drugs that “may_treat” the DISEASE class COVID-19? Explore the RxClass browser by entering “COVID-19” in the RxClass browser search bar, clicking "COVID-19" under "DISEASE", then click on a class hierarchy: https://mor.nlm.nih.gov/RxClass/
Learn more about RxClass and other web-based drug information resources on the RxNav landing page: https://rxnav.nlm.nih.gov/
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 437 |
| Active BPCKs | 522 |
| Active SCDs | 16477 |
| Active SBDs | 9455 |
| Active RXNORM MINs | 3739 |
| Active RXNORM INs | 13254 |
| Active RXNORM PINs | 3105 |
| Active RXNORM BNs | 5149 |
| Active RXNORM DFs | 121 |
| Obsolete GPCKs | 235 |
| Obsolete BPCKs | 202 |
| Obsolete SCDs | 18793 |
| Obsolete SBDs | 10772 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6100 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 1804 |
| Editor-suppressed SBDs | 1486 |
| SAB=RXNORM NDCs | 250675 |
| Distinct SAB=RXNORM NDCs | 250675 |
Last Reviewed: April 5, 2021