October Release - 10/02/2023
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | Source Abbreviation (SAB) | Version |
|---|---|---|
| Vaccines Administered | CVX | CVX_2023_09_20 |
| DrugBank | DRUGBANK | DRUGBANK5.0_2023_09_08 |
| Gold Standard Drug Database | GS | GS_2023_09_07 |
| Multum MediSource Lexicon | MMSL | MMSL_2023_09_01 |
| Micromedex RED BOOK | MMX | MMX_2023_09_04 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2023_09_22 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2023_09_06 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_231002F |
| Veterans Health Administration National Drug File | VANDF | VANDF_2023_08_31 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2023_03_21 |
| Medical Subject Headings (MeSH) | MSH | MSH2023_2022_07_27 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2023_06_30 |
| USP Compendial Nomenclature | USP | USP_2023_08_17 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RxNorm Data Changes
Changes to Xacduro
In response to CDC National Healthcare Safety Network (NHSN) feedback regarding issues with antimicrobial use surveillance and the modeling of Xacduro in RxNorm, we have changed Xacduro to a Semantic Branded Drug (SBD) for the RxNorm October 2023 monthly release. The concepts have new RXCUIs shown below.
New modeling:
| RXCUI | Term Type (TTY) | String |
|---|---|---|
| 2665012 | SCD | durlobactam 1000 MG / sulbactam 1000 MG Injection |
| 2665017 | SBD | durlobactam 1000 MG / sulbactam 1000 MG Injection [Xacduro] |
Previous modeling:
| RXCUI | Term Type (TTY) | String |
|---|---|---|
| 2639100 | GPCK | {2 (durlobactam 500 MG Injection) / 1 (sulbactam 1000 MG Injection) } Pack |
| 2639101 | BPCK | {2 (durlobactam 500 MG Injection) / 1 (sulbactam 1000 MG Injection) } Pack [Xacduro] |
Changes to Tacrolimus Products
The FDA has changed the therapeutic equivalence rating of some tacrolimus products to BX. Based on feedback from our users, we have created new normal forms for those with the qualitative distinction of BX.
The new forms are:
| RXCUI | Term Type (TTY) | String |
|---|---|---|
| 2665161 | SCD | BX Rating tacrolimus 0.5 MG Oral Capsule |
| 2665162 | SCD | BX Rating tacrolimus 1 MG Oral Capsule |
| 2665163 | SCD | BX Rating tacrolimus 5 MG Oral Capsule |
The old forms are still available:
| RXCUI | Term Type (TTY) | String |
|---|---|---|
| 313190 | SCD | tacrolimus 0.5 MG Oral Capsule |
| 198377 | SCD | tacrolimus 1 MG Oral Capsule |
| 198378 | SCD | tacrolimus 5 MG Oral Capsule |
For more information about the FDA’s decision see: https://www.fda.gov/drugs/drug-safety-and-availability/fda-changing-therapeutic-equivalence-rating-accord-healthcare-incs-generics-prograf-tacrolimus-oral.
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 581 |
| Active BPCKs | 684 |
| Active SCDs | 17164 |
| Active SBDs | 9547 |
| Active RXNORM MINs | 3785 |
| Active RXNORM INs | 14204 |
| Active RXNORM PINs | 3428 |
| Active RXNORM BNs | 5110 |
| Active RXNORM DFs | 123 |
| Obsolete GPCKs | 245 |
| Obsolete BPCKs | 231 |
| Obsolete SCDs | 19315 |
| Obsolete SBDs | 11528 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6331 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 2002 |
| Editor-suppressed SBDs | 1665 |
| SAB=RXNORM NDCs | 243228 |
| Distinct SAB=RXNORM NDCs | 243228 |
Last Reviewed: September 29, 2023