November Release - 11/06/2023
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | Source Abbreviation (SAB) | Version |
|---|---|---|
| Vaccines Administered | CVX | CVX_2023_10_11 |
| DrugBank | DRUGBANK | DRUGBANK5.0_2023_10_06 |
| Gold Standard Drug Database | GS | GS_2023_10_05 |
| Multum MediSource Lexicon | MMSL | MMSL_2023_10_01 |
| Micromedex RED BOOK | MMX | MMX_2023_10_01 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2023_10_26 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2023_10_04 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_231106F |
| Veterans Health Administration National Drug File | VANDF | VANDF_2023_09_29 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2023_03_21 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2023_06_30 |
| USP Compendial Nomenclature | USP | USP_2023_08_17 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RxNorm Data Changes
Removal of MeSH from RxNorm
As previously announced on April 4, 2023, the National Library of Medicine (NLM) will no longer include MeSH (SAB=MSH) in the RxNorm data files starting with the RxNorm November 6, 2023 monthly release. NLM is removing MeSH from RxNorm to better focus development efforts on clinical drug vocabularies in RxNorm. The RxNorm October 2, 2023 monthly release will be the last RxNorm release to contain MeSH content.
MeSH and RxNorm content will continue to be available in the Unified Medical Language System (UMLS). The UMLS Metathesaurus MRCONSO file connects MeSH and RxNorm content via a UMLS Concept Unique Identifier (CUI). RxNorm RXCUIs are represented in the CODE field in the MRCONSO file. The following query demonstrates how MeSH and RxNorm are connected in the UMLS Metathesaurus:
select mc1.cui, mc1.sab, mc1.tty, mc1.code as rxcui, mc1.str, mc2.sab, mc2.scui, mc2.sdui, mc2.sab, mc2.tty, mc2.str
from mrconso mc1, mrconso mc2
where mc1.cui = mc2.cui
and mc1.sab='RXNORM'
and mc1.tty not in ('TMSY','SY','PSN')
and mc2.sab='MSH'
order by mc1.cui;
More information about MeSH: https://www.nlm.nih.gov/mesh/meshhome.html.
More information about UMLS: https://www.nlm.nih.gov/research/umls/index.html.
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 585 |
| Active BPCKs | 689 |
| Active SCDs | 17196 |
| Active SBDs | 9559 |
| Active RXNORM MINs | 3787 |
| Active RXNORM INs | 14240 |
| Active RXNORM PINs | 3439 |
| Active RXNORM BNs | 5112 |
| Active RXNORM DFs | 123 |
| Obsolete GPCKs | 242 |
| Obsolete BPCKs | 228 |
| Obsolete SCDs | 19333 |
| Obsolete SBDs | 11561 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6351 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 2012 |
| Editor-suppressed SBDs | 1674 |
| SAB=RXNORM NDCs | 244355 |
| Distinct SAB=RXNORM NDCs | 244355 |
Last Reviewed: November 6, 2023