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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

January Release - 01/06/2025

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.

Sources

The following sources with version names in bold have been updated since the previous RxNorm release:

Source Name Source Abbreviation (SAB) Version
DrugBank DRUGBANK DRUGBANK5.0_2024_12_05
Gold Standard Drug Database GS GS_2024_12_06
Multum MediSource Lexicon MMSL MMSL_2024_12_01
Micromedex RED BOOK MMX MMX_2024_11_30
FDA Structured Product Labels MTHSPL MTHSPL_2024_12_26
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2024_12_04
RxNorm normalized names and codes RXNORM RXNORM_20AA_250106F
Veterans Health Administration National Drug File VANDF VANDF_2024_11_29

The following sources have not been updated since the previous RxNorm release:

Source Name Source Abbreviation (SAB) Version
Anatomical Therapeutic Chemical Classification System ATC ATC_2024_01_19
Vaccines Administered CVX CVX_2024_10_24
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2024_07_31
USP Compendial Nomenclature USP USP_2024_07_10

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.


RxNorm Data Changes

New Qualitative Distinction: Shortage Import Unapproved

We have added a new Qualitative Distinction (Shortage Import Unapproved) in cases where the label indicates that the FDA does not consider the product to be directly substitutable with the product manufactured in the United States. For example:

US Products:

RXCUITTYSTR
1795610SCD250 ML glucose 50 MG/ML Injection
1795610PSNdextrose 5 % in 250 ML Injection
1795610SYdextrose 5 % per 250 ML Injection
1795612SCD1000 ML glucose 50 MG/ML Injection
1795612PSNdextrose 5 % in 1000 ML Injection
1795612SYdextrose 5 % per 1000 ML Injection

Imported Products:

RXCUITTYSTR
2698220SCDShortage Import Unapproved 250 ML glucose 50 MG/ML Injection
2698220PSNdextrose 5 % in 250 ML Injection, Shortage Import Unapproved
2698220SYdextrose 5 % per 250 ML Injection, Shortage Import Unapproved
2698221SCDShortage Import Unapproved 1000 ML glucose 50 MG/ML Injection
2698221PSNdextrose 5 % in 1000 ML Injection, Shortage Import Unapproved
2698221SYdextrose 5 % per 1000 ML Injection, Shortage Import Unapproved

See the HEALTH CARE PROFESSIONAL LETTER in DailyMed for more information: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=40c99503-14fd-4cd1-b073-c1af7bfa3229

For more information about Qualitative Distinctions in RxNorm, see: https://www.nlm.nih.gov/research/umls/rxnorm/docs/techdoc.html#s10_3



Data Counts

Term Type or AttributeNumber
Active GPCKs618
Active BPCKs711
Active SCDs17494
Active SBDs9640
Active RXNORM MINs3804
Active RXNORM INs14492
Active RXNORM PINs3523
Active RXNORM BNs5099
Active RXNORM DFs122
  
Obsolete GPCKs252
Obsolete BPCKs238
Obsolete SCDs19530
Obsolete SBDs11826
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6477
Obsolete RXNORM DFs64
Editor-suppressed SCDs2080
Editor-suppressed SBDs1736
SAB=RXNORM NDCs253193
Distinct SAB=RXNORM NDCs253193

Last Reviewed: January 6, 2025