Marsh Test Apparatus, Steel engraving, 1867
Theodore G. Wormeley, M.D., Microchemistry of Poisons, including their Physiological, Pathological, and Legal Relations, New York
National Library of Medicine
In 1832 police arrested John Bodle for lacing his grandfather's coffee with poison. Chemist James Marsh tested the drink in his laboratory, and confirmed the presence of arsenic by producing a yellow precipitate of arsenic sulfide. But the precipitate was unstable and, by the time of trial, had deteriorated. Without forensic proof, Bodle was acquitted. Stung by the verdict, Marsh devised a test that could better stand up in court. His 1836 "Marsh Test" won worldwide acclaim and became a standard procedure. But in subsequent decades Marsh's test was shown to be problematic, and in turn underwent a series of improvements.