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Applications of the Visible Human Male Data Set in Electrocardiology: Simulation
of the Electrical Excitation Propagation
Abstract
Due to its high spatial resolution the Visible Man
dataset provides a good possibility to simulate certain aspects of human
physiology based on detailed, macroscopic models of the human anatomy.
This study deals with the simulation of the electrical excitation propagation
in the human heart. Along with applications in education, diagnosis and
therapy, this simulation is used in manifold fields of research, such as
solving the forward problem of electrocardiography with a realistic boundary
condition or validating solutions of the inverse problem of electrocardiography.
The simulation is based on an anatomical and physiologocal model of
the heart of the Visible Man. The anatomical model was created exploring
the data provided with the thin-section photos of the Visible Man dataset.
The simulation of the electrical excitation propagation was performed by
a cellular automaton which combines the anatomical model with physiological
parameters of the electrical excitation propagation. It allowed to calculated
the electrical source distribution in the heart numerically which was used
to solve the forward problem of electrocardiology which is the calculation
of body surface potential maps from a given source distribution.
Keywords: heart, electrical propagation, surface potential maps.
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