Breakout: Genome Exploration & Visualization
Today, we will be focusing on the following visualization tools:
Genome Data Viewer: GDV is a genome browser supporting the exploration and analysis of more than 3070 eukaryotic RefSeq genome assemblies. The GDV browser displays biological information mapped to a genome, including gene annotation, variation data, BLAST alignments, and experimental study data from the NCBI GEO and dbGaP databases.
Comparative Genome Viewer (CGV): visualizes eukaryotic whole genome assembly-assembly alignments. You can choose from a selection of alignments that are provided by NCBI.
Here are some possible use cases we can explore today!
Example page for today: here
Using GDV to Visualize Eukaryotic Genomic Data
View slides and handouts
Visualizing the genetic cause of a lethal disorder in cattle
See how a gene deletion causes phenotypic differences in barley
Using GDV for analysis of human variation:
Explore missense mutations related to neurological disorders
Examine alternative genomic diagnoses for an X-linked phenotype
Link to page
View recording and description
View Handout
View Slides
Using GDV for visualizing gene expression:
Please note that the Jupyter notebook on the above page may take several minutes to load
Visualize gene expression differences between control and affected individuals with progeria
Exploring the Relationship Between Two Eukaryotic Genomes Using the Comparative Genome Viewer
Click link above to investigate the following:Compare the human T2T CHM3 assembly to the current reference assembly, GRCh38.14
Explore the extent of gene order conservation (synteny) between two organisms
Last Reviewed: August 7, 2024